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Pianorm (Pioglitazone)

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Pianorm works by making cells more sensitive to insulin, which is used to regulate the level of glucose in the body. Improving insulin sensitivity (or reducing insulin resistance) makes it easier for sugar (glucose) in the blood to get into the cells.

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Also known as: Pioglitazone


Pianorm (pioglitazone) is an oral diabetes medicine that helps control blood sugar levels.

Pianorm is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Pianorm is not for treating type 1 diabetes.


Take Pianorm by mouth with a full glass of water with or without food. The initial dose of Pianorm is 15 mg once a day. In case of inadequate glycemic control, the dose can be increased up to 45 mg once daily. If hypoglycemia occurs in a patient co-administering Pianorm and insulin, the dose of insulin should be decreased by 10% to 25%. Further adjustments to the insulin dose should be individualized based on glycemic response. Take the drug at the same time each day. If you want to achieve the most effective results, do not stop taking Pianorm suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Pianorm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Pianorm if you are allergic to pioglitazone, or if you have:

severe or uncontrolled heart failure; or diabetic ketoacidosis (call your doctor for treatment).

This medication may increase your risk of developing bladder cancer. Talk with your doctor about your specific risk.

To make sure Pianorm is safe for you, tell your doctor if you have ever had:

congestive heart failure or heart disease; a heart attack or stroke; eye problems caused by diabetes; bladder cancer; or liver disease.

Pianorm may increase your risk of serious heart problems, but not treating your diabetes can also damage your heart and other organs. Talk to your doctor about the risks and benefits of this medicine.

Follow your doctor's instructions about using Pianorm if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

Pioglitazone may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

Women may be more likely to have a broken bone while using Pianorm. Talk with your doctor about ways to keep your bones healthy.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Pianorm is not approved for use by anyone younger than 18 years old.

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The galactose-particle receptor mediates uptake via coated and also non-coated structures. The marginal mandibular nerve was injured in three patients and recurrent laryngeal nerve dysfunction was noted in four patients. This article describes laser systems used for scar treatment according to scar type, evaluates the highest available level of evidence from randomized controlled trials (RCTs) and introduces a guideline for laser treatment of scars. Our findings indicate that abnormal brain activity is mainly distributed within prefrontal-limbic circuits, which are believed to be involved in the pathophysiological mechanisms underlying bipolar depression. The implications of these results on the stimulus level dependence of SFOAE fine structure are also explored. Rats with compression injury surviving 4 or 9 days showed apoptotic glial cells in the longitudinal tracts of the Th8-9, the cranial Th7, and the caudal Th10 segments. Owing to their paracrine, differentiation and self-renewal abilities, mesenchymal stem cells (MSCs) have great potential for regenerative medicine, which might be further enhanced by targeted gene therapy. The advantage the Wagner device affords over conventional traction devices and other external fixation units makes its use a viable orthopaedic alternative. To elucidate the role of CTGF in fibrovascular proliferative retinopathy, we investigated the regulation of CTGF gene expression in a cell line of retinal vascular endothelial cells (RVEC) stimulated with fetal calf serum (FCS) and angiogenic growth factors, including vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), platelet-derived growth factor-BB (PDGF-BB), endothelial growth factor (EGF), transforming growth factor-beta 1 and -beta 3 (TGF-beta 1, TGF-beta 3), and insulin-like growth factor-I (IGF-I).

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Results following bands and ligatures on the human internal carotid artery. The adverse effects of estrogen and selective estrogen receptor modulators on hemostasis and thrombosis. The military and civilian nuclear activities in the former Soviet Union led to unique exposures and resulted in high cumulative doses in several populations. Integrated community case management (iCCM) is a recommended strategy to curb child mortality. Patients with thoracic compression fractures received significant long-lasting relief after receiving fluoroscopically guided intra-articular injections. A nuclear-encoded mitochondrial gene AtCIB22 is essential for plant development in Arabidopsis.

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Influence of sympatho-vagal balance on airway responsiveness in athletes. An assessment of some hazards associated with the collection of venous blood. In this report, we describe the clinical features of a transthyretin (TTR) gene mutation (Asp18Asn) in a 54-year-old Liberian male what over the counter medicine is equivalent to protonix presenting with congestive heart failure due to amyloid cardiomyopathy, in the absence of neurologic impairment. Of great interest are blood eosinophils since current data support their role either as tool for treatment selections or/and as a biomarker of airway eosinophilia. Gastric Cancer Patients with High PLK1 Expression and DNA Aneuploidy Correlate with Poor Prognosis. Significance of the electroencephalographic changes in hepatic coma.

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Two-Dimensional Titanium Carbide/RGO Composite for High-Performance Supercapacitors. The rationale, indications of above regimens and cautions necessary are highlighted. These findings indicate that adolescents in this rural population are still practising high risk sexual behaviours suggesting the need for youth-targeted intervention programmes in rural Tanzania. Negative correlations of the Q-LES-Q domains with clinical scales (Dissociative Experiences Scale, BDI, Beck Anxiety Inventory, Sheehan Anxiety Scale, Clinical Global Impression, and SDS) are noticeable. Logistic regression analysis indicated that factors independently associated (p less than or equal to 0.05) with a higher risk of catheter-acquired bacteriuria were as follows: hospitalization in orthopedics or urology, ethnic origin (Arabs greater than Jews), insertion of a catheter after the sixth day of hospitalization, catheterization outside the operating theatres, lack of administration of systemic antibiotics, unsatisfactory catheter care, and prolonged duration (greater than or equal to 7 days) of tenormin tablet price in pakistan catheterization before infection occurred. We employ nonstandard statistical methods to treat the inverse prediction, which has an infinite mean and variance due to the presence of a normally distributed variable in the denominator. Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma.

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